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Constitutive activity of NF-kappa B in myeloid cells drives pathogenicity of monocytes and macrophages during autoimmune neuroinflammation

The NF-κB/REL-family of transcription factors plays a central role in coordinating the expression of a wide variety of genes controlling immune responses including autoimmunity of the central nervous system (CNS). The inactive form of NF-κB consists of a heterodimer which is complexed with its inhib...

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Detalles Bibliográficos
Autores principales: Ellrichmann, Gisa, Thöne, Jan, Lee, De-Hyung, Rupec, Rudolph A, Gold, Ralf, Linker, Ralf A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3274436/
https://www.ncbi.nlm.nih.gov/pubmed/22260436
http://dx.doi.org/10.1186/1742-2094-9-15