Protein dynamics at Eph receptor-ligand interfaces as revealed by crystallography, NMR and MD simulations

BACKGROUND: The role of dynamics in protein functions including signal transduction is just starting to be deciphered. Eph receptors with 16 members divided into A- and B- subclasses are respectively activated by 9 A- and B-ephrin ligands. EphA4 is the only receptor capable of binding to all 9 ephri...

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Detalles Bibliográficos
Autores principales: Qin, Haina, Lim, Liangzhong, Song, Jianxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3274464/
https://www.ncbi.nlm.nih.gov/pubmed/22277260
http://dx.doi.org/10.1186/2046-1682-5-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3274464/
https://www.ncbi.nlm.nih.gov/pubmed/22277260
http://dx.doi.org/10.1186/2046-1682-5-2

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