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Reproducibility of quantitative (R)-[(11)C]verapamil studies

BACKGROUND: P-glycoprotein [Pgp] dysfunction may be involved in neurodegenerative diseases, such as Alzheimer's disease, and in drug resistant epilepsy. Positron emission tomography using the Pgp substrate tracer (R)-[(11)C]verapamil enables in vivo quantification of Pgp function at the human b...

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Detalles Bibliográficos
Autores principales: van Assema, Daniëlle ME, Lubberink, Mark, Boellaard, Ronald, Schuit, Robert C, Windhorst, Albert D, Scheltens, Philip, van Berckel, Bart NM, Lammertsma, Adriaan A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3274480/
https://www.ncbi.nlm.nih.gov/pubmed/22251281
http://dx.doi.org/10.1186/2191-219X-2-1