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Sources of Dietary Protein in Relation to Blood Pressure in a General Dutch Population

BACKGROUND: Little is known about the relation of different dietary protein types with blood pressure (BP). We examined whether intake of total, plant, animal, dairy, meat, and grain protein was related to BP in a cross sectional cohort of 20,820 Dutch adults, aged 20–65 y and not using antihyperten...

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Autores principales: Altorf - van der Kuil, Wieke, Engberink, Mariëlle F., Vedder, Moniek M., Boer, Jolanda M. A., Verschuren, W. M. Monique, Geleijnse, Johanna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3274530/
https://www.ncbi.nlm.nih.gov/pubmed/22347387
http://dx.doi.org/10.1371/journal.pone.0030582
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author Altorf - van der Kuil, Wieke
Engberink, Mariëlle F.
Vedder, Moniek M.
Boer, Jolanda M. A.
Verschuren, W. M. Monique
Geleijnse, Johanna M.
author_facet Altorf - van der Kuil, Wieke
Engberink, Mariëlle F.
Vedder, Moniek M.
Boer, Jolanda M. A.
Verschuren, W. M. Monique
Geleijnse, Johanna M.
author_sort Altorf - van der Kuil, Wieke
collection PubMed
description BACKGROUND: Little is known about the relation of different dietary protein types with blood pressure (BP). We examined whether intake of total, plant, animal, dairy, meat, and grain protein was related to BP in a cross sectional cohort of 20,820 Dutch adults, aged 20–65 y and not using antihypertensive medication. DESIGN: Mean BP levels were calculated in quintiles of energy-adjusted protein with adjustment for age, sex, BMI, education, smoking, and intake of energy, alcohol, and other nutrients including protein from other sources. In addition, mean BP difference after substitution of 3 en% carbohydrates or MUFA with protein was calculated. RESULTS: Total protein and animal protein were not associated with BP (p(trend) = 0.62 and 0.71 respectively), both at the expense of carbohydrates and MUFA. Systolic BP was 1.8 mmHg lower (p(trend)<0.01) in the highest (>36 g/d) than in the lowest (<27 g/d) quintile of plant protein. This inverse association was present both at the expense of carbohydrates and MUFA and more pronounced in individuals with untreated hypertension (−3.6 mmHg) than in those with normal (+0.1 mmHg) or prehypertensive BP (−0.3 mmHg; p(interaction)<0.01). Meat and grain protein were not related to BP. Dairy protein was directly associated with systolic BP (+1.6 mmHg, p(trend)<0.01), but not with diastolic BP (p(trend) = 0.24). CONCLUSIONS: Total protein and animal protein were not associated with BP in this general untreated Dutch population. Plant protein may be beneficial to BP, especially in people with elevated BP. However, because high intake of plant protein may be a marker of a healthy diet and lifestyle in general, confirmation from randomized controlled trials is warranted.
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spelling pubmed-32745302012-02-15 Sources of Dietary Protein in Relation to Blood Pressure in a General Dutch Population Altorf - van der Kuil, Wieke Engberink, Mariëlle F. Vedder, Moniek M. Boer, Jolanda M. A. Verschuren, W. M. Monique Geleijnse, Johanna M. PLoS One Research Article BACKGROUND: Little is known about the relation of different dietary protein types with blood pressure (BP). We examined whether intake of total, plant, animal, dairy, meat, and grain protein was related to BP in a cross sectional cohort of 20,820 Dutch adults, aged 20–65 y and not using antihypertensive medication. DESIGN: Mean BP levels were calculated in quintiles of energy-adjusted protein with adjustment for age, sex, BMI, education, smoking, and intake of energy, alcohol, and other nutrients including protein from other sources. In addition, mean BP difference after substitution of 3 en% carbohydrates or MUFA with protein was calculated. RESULTS: Total protein and animal protein were not associated with BP (p(trend) = 0.62 and 0.71 respectively), both at the expense of carbohydrates and MUFA. Systolic BP was 1.8 mmHg lower (p(trend)<0.01) in the highest (>36 g/d) than in the lowest (<27 g/d) quintile of plant protein. This inverse association was present both at the expense of carbohydrates and MUFA and more pronounced in individuals with untreated hypertension (−3.6 mmHg) than in those with normal (+0.1 mmHg) or prehypertensive BP (−0.3 mmHg; p(interaction)<0.01). Meat and grain protein were not related to BP. Dairy protein was directly associated with systolic BP (+1.6 mmHg, p(trend)<0.01), but not with diastolic BP (p(trend) = 0.24). CONCLUSIONS: Total protein and animal protein were not associated with BP in this general untreated Dutch population. Plant protein may be beneficial to BP, especially in people with elevated BP. However, because high intake of plant protein may be a marker of a healthy diet and lifestyle in general, confirmation from randomized controlled trials is warranted. Public Library of Science 2012-02-07 /pmc/articles/PMC3274530/ /pubmed/22347387 http://dx.doi.org/10.1371/journal.pone.0030582 Text en Altorf - van der Kuil et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Altorf - van der Kuil, Wieke
Engberink, Mariëlle F.
Vedder, Moniek M.
Boer, Jolanda M. A.
Verschuren, W. M. Monique
Geleijnse, Johanna M.
Sources of Dietary Protein in Relation to Blood Pressure in a General Dutch Population
title Sources of Dietary Protein in Relation to Blood Pressure in a General Dutch Population
title_full Sources of Dietary Protein in Relation to Blood Pressure in a General Dutch Population
title_fullStr Sources of Dietary Protein in Relation to Blood Pressure in a General Dutch Population
title_full_unstemmed Sources of Dietary Protein in Relation to Blood Pressure in a General Dutch Population
title_short Sources of Dietary Protein in Relation to Blood Pressure in a General Dutch Population
title_sort sources of dietary protein in relation to blood pressure in a general dutch population
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3274530/
https://www.ncbi.nlm.nih.gov/pubmed/22347387
http://dx.doi.org/10.1371/journal.pone.0030582
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