Identification of Estrogen Receptor Dimer Selective Ligands Reveals Growth-Inhibitory Effects on Cells That Co-Express ERα and ERβ

Estrogens play essential roles in the progression of mammary and prostatic diseases. The transcriptional effects of estrogens are transduced by two estrogen receptors, ERα and ERβ, which elicit opposing roles in regulating proliferation: ERα is proliferative while ERβ is anti-proliferative. Exogenou...

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Detalles Bibliográficos
Autores principales: Powell, Emily, Shanle, Erin, Brinkman, Ashley, Li, Jun, Keles, Sunduz, Wisinski, Kari B., Huang, Wei, Xu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3274540/
https://www.ncbi.nlm.nih.gov/pubmed/22347418
http://dx.doi.org/10.1371/journal.pone.0030993

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3274540/
https://www.ncbi.nlm.nih.gov/pubmed/22347418
http://dx.doi.org/10.1371/journal.pone.0030993

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