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Ameliorated ConA-Induced Hepatitis in the Absence of PKC-theta

Severe liver injury that occurs when immune cells mistakenly attack an individual's own liver cells leads to autoimmune hepatitis. In mice, acute hepatitis can be induced by concanavalin A (ConA) treatment, which causes rapid activation of CD1d-positive natural killer (NK) T cells. These activa...

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Detalles Bibliográficos
Autores principales: Fang, Xianfeng, Wang, Ruiqing, Ma, Jian, Ding, Yan, Shang, Weirong, Sun, Zuoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3274545/
https://www.ncbi.nlm.nih.gov/pubmed/22347449
http://dx.doi.org/10.1371/journal.pone.0031174