Cargando…

The impact of caspase-12 on susceptibility to candidemia

Candida is one of the leading causes of sepsis, and an effective host immune response to Candida critically depends on the cytokines IL-1β and IL-18, which need caspase-1 cleavage to become bioactive. Caspase-12 has been suggested to inhibit caspase-1 activation and has been implicated as a suscepti...

Descripción completa

Detalles Bibliográficos
Autores principales: Rosentul, D. C., Plantinga, T. S., Scott, W. K., Alexander, B. D., van de Geer, N. M. D., Perfect, J. R., Kullberg, B. J., Johnson, M. D., Netea, M. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3274675/
https://www.ncbi.nlm.nih.gov/pubmed/21706251
http://dx.doi.org/10.1007/s10096-011-1307-x