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Chemical labelling of active serum thioester proteins for quantification

The complement serum proteins C3 and C4 and the protease inhibitor α-2 macroglobulin are all members of the C3/α-2M thioester protein family, an evolutionarily ancient and conserved family that contains an intrachain thioester bond. The chemistry of the thioester bond is a key to the function of the...

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Detalles Bibliográficos
Autores principales: Holm, Lotta, Ackland, Gareth L., Edwards, Mark R., Breckenridge, Ross A., Sim, Robert B., Offer, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3274692/
https://www.ncbi.nlm.nih.gov/pubmed/21852021
http://dx.doi.org/10.1016/j.imbio.2011.07.021