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Altered synaptic marker abundance in the hippocampal stratum oriens of Ts65Dn mice is associated with exuberant expression of versican

DS (Down syndrome), resulting from trisomy of chromosome 21, is the most common cause of genetic mental retardation; however, the molecular mechanisms underlying the cognitive deficits are poorly understood. Growing data indicate that changes in abundance or type of CSPGs (chondroitin sulfate proteo...

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Detalles Bibliográficos
Autores principales: Howell, Matthew D, Gottschall, Paul E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Neurochemistry 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275338/
https://www.ncbi.nlm.nih.gov/pubmed/22225533
http://dx.doi.org/10.1042/AN20110037