Non-cell autonomous influence of the astrocyte system x(c)(−) on hypoglycaemic neuronal cell death

Despite longstanding evidence that hypoglycaemic neuronal injury is mediated by glutamate excitotoxicity, the cellular and molecular mechanisms involved remain incompletely defined. Here, we demonstrate that the excitotoxic neuronal death that follows GD (glucose deprivation) is initiated by glutama...

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Detalles Bibliográficos
Autores principales: Jackman, Nicole A, Melchior, Shannon E, Hewett, James A, Hewett, Sandra J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Neurochemistry 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275339/
https://www.ncbi.nlm.nih.gov/pubmed/22220511
http://dx.doi.org/10.1042/AN20110030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275339/
https://www.ncbi.nlm.nih.gov/pubmed/22220511
http://dx.doi.org/10.1042/AN20110030

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