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Invasive matrix degradation at focal adhesions occurs via protease recruitment by a FAK–p130Cas complex

Tumor cell migration and the concomitant degradation of extracellular matrix (ECM) are two essential steps in the metastatic process. It is well established that focal adhesions (FAs) play an important role in regulating migration; however, whether these structures contribute to matrix degradation i...

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Detalles Bibliográficos
Autores principales: Wang, Yu, McNiven, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275373/
https://www.ncbi.nlm.nih.gov/pubmed/22291036
http://dx.doi.org/10.1083/jcb.201105153