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Invasive matrix degradation at focal adhesions occurs via protease recruitment by a FAK–p130Cas complex
Tumor cell migration and the concomitant degradation of extracellular matrix (ECM) are two essential steps in the metastatic process. It is well established that focal adhesions (FAs) play an important role in regulating migration; however, whether these structures contribute to matrix degradation i...
Autores principales: | Wang, Yu, McNiven, Mark A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275373/ https://www.ncbi.nlm.nih.gov/pubmed/22291036 http://dx.doi.org/10.1083/jcb.201105153 |
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