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ESR1, HK3 and BRSK1 gene variants are associated with both age at natural menopause and premature ovarian failure

BACKGROUND: Premature ovarian failure (POF) is a complex and heterogeneous disorder that is influenced by multiple genetic components. Numerous candidate gene studies designed to identify POF susceptibility loci have been published, but most positive findings have not been confirmed in follow up stu...

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Detalles Bibliográficos
Autores principales: Qin, Yingying, Sun, Mei, You, Li, Wei, Deying, Sun, Jielin, Liang, Xiaoyan, Zhang, Bo, Jiang, Hong, Xu, Jianfeng, Chen, Zi-Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275465/
https://www.ncbi.nlm.nih.gov/pubmed/22248077
http://dx.doi.org/10.1186/1750-1172-7-5