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The MLH1 2101C>A (Q701K) variant increases the risk of gastric cancer in Chinese males

BACKGROUND: Gastric cancer is one of the most common cancers affecting East Asians, and MLH1 could play a critical role during tumorigenesis in this condition. METHODS: Samples from 236 Chinese patients suffering from gastric cancer were screened for MLH1 germline mutations. Carrier frequencies of t...

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Detalles Bibliográficos
Autores principales: Zhi, Wenxian, Xue, Binshuang, Wang, Lifeng, Xiao, Nong, He, Qiong, Wang, Yaping, Fan, Yimei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275522/
https://www.ncbi.nlm.nih.gov/pubmed/22136435
http://dx.doi.org/10.1186/1471-230X-11-133