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Regulation of Cyclooxygenase-2 Expression by Heat: A Novel Aspect of Heat Shock Factor 1 Function in Human Cells

The heat-shock response, a fundamental defense mechanism against proteotoxic stress, is regulated by a family of heat-shock transcription factors (HSF). In humans HSF1 is considered the central regulator of heat-induced transcriptional responses. The main targets for HSF1 are specific promoter eleme...

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Detalles Bibliográficos
Autores principales: Rossi, Antonio, Coccia, Marta, Trotta, Edoardo, Angelini, Mara, Santoro, M. Gabriella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275557/
https://www.ncbi.nlm.nih.gov/pubmed/22347460
http://dx.doi.org/10.1371/journal.pone.0031304