Determining PTEN Functional Status by Network Component Deduced Transcription Factor Activities

PTEN-controlled PI3K-AKT-mTOR pathway represents one of the most deregulated signaling pathways in human cancers. With many small molecule inhibitors that target PI3K-AKT-mTOR pathway being exploited clinically, sensitive and reliable ways of stratifying patients according to their PTEN functional s...

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Detalles Bibliográficos
Autores principales: Tran, Linh M., Chang, Chun-Ju, Plaisier, Seema, Wu, Shumin, Dang, Julie, Mischel, Paul S., Liao, James C., Graeber, Thomas G., Wu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275574/
https://www.ncbi.nlm.nih.gov/pubmed/22347425
http://dx.doi.org/10.1371/journal.pone.0031053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275574/
https://www.ncbi.nlm.nih.gov/pubmed/22347425
http://dx.doi.org/10.1371/journal.pone.0031053

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