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Shortening of 3′UTRs Correlates with Poor Prognosis in Breast and Lung Cancer
A major part of the post-transcriptional regulation of gene expression is affected by trans-acting elements, such as microRNAs, binding the 3′ untraslated region (UTR) of their target mRNAs. Proliferating cells partly escape this type of negative regulation by expressing shorter 3′ UTRs, depleted of...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275581/ https://www.ncbi.nlm.nih.gov/pubmed/22347440 http://dx.doi.org/10.1371/journal.pone.0031129 |