Cargando…
Shortening of 3′UTRs Correlates with Poor Prognosis in Breast and Lung Cancer
A major part of the post-transcriptional regulation of gene expression is affected by trans-acting elements, such as microRNAs, binding the 3′ untraslated region (UTR) of their target mRNAs. Proliferating cells partly escape this type of negative regulation by expressing shorter 3′ UTRs, depleted of...
Autores principales: | Lembo, Antonio, Di Cunto, Ferdinando, Provero, Paolo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275581/ https://www.ncbi.nlm.nih.gov/pubmed/22347440 http://dx.doi.org/10.1371/journal.pone.0031129 |
Ejemplares similares
-
Identification of candidate regulatory sequences in mammalian 3' UTRs by statistical analysis of oligonucleotide distributions
por: Corà, Davide, et al.
Publicado: (2007) -
A Signature Inferred from Drosophila Mitotic Genes
Predicts Survival of Breast Cancer Patients
por: Damasco, Christian, et al.
Publicado: (2011) -
Correlating overrepresented upstream motifs to gene expression: a computational approach to regulatory element discovery in eukaryotes
por: Caselle, Michele, et al.
Publicado: (2002) -
CLOE: Identification of putative functional relationships among genes by comparison of expression profiles between two species
por: Pellegrino, Maurizio, et al.
Publicado: (2004) -
Drug repositioning for orphan genetic diseases through Conserved Anticoexpressed Gene Clusters (CAGCs)
por: Molineris, Ivan, et al.
Publicado: (2013)