Characterization of Ku702–NLS as Bipartite Nuclear Localization Sequence for Non-Viral Gene Delivery

Several barriers have to be overcome in order to achieve gene expression in target cells, e.g. cellular uptake, endosomal release and translocation to the nucleus. Nuclear localization sequences (NLS) enhance gene delivery by increasing the uptake of plasmid DNA (pDNA) to the nucleus. So far, only m...

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Detalles Bibliográficos
Autores principales: Matschke, Johannes, Bohla, Alexander, Maucksch, Christof, Mittal, Rashmi, Rudolph, Carsten, Rosenecker, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275586/
https://www.ncbi.nlm.nih.gov/pubmed/22347357
http://dx.doi.org/10.1371/journal.pone.0024615

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275586/
https://www.ncbi.nlm.nih.gov/pubmed/22347357
http://dx.doi.org/10.1371/journal.pone.0024615

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