Cargando…

Characterization of Ku702–NLS as Bipartite Nuclear Localization Sequence for Non-Viral Gene Delivery

Several barriers have to be overcome in order to achieve gene expression in target cells, e.g. cellular uptake, endosomal release and translocation to the nucleus. Nuclear localization sequences (NLS) enhance gene delivery by increasing the uptake of plasmid DNA (pDNA) to the nucleus. So far, only m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Matschke, Johannes, Bohla, Alexander, Maucksch, Christof, Mittal, Rashmi, Rudolph, Carsten, Rosenecker, Joseph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275586/ https://www.ncbi.nlm.nih.gov/pubmed/22347357 http://dx.doi.org/10.1371/journal.pone.0024615

Ejemplares similares

Cell type differences in activity of the Streptomyces bacteriophage ϕC31 integrase
por: Maucksch, Christof, et al.
Publicado: (2008)

Nuclear Localization of the DNA Repair Scaffold XRCC1: Uncovering the Functional Role of a Bipartite NLS
por: Kirby, Thomas W., et al.
Publicado: (2015)

Structural Characterisation of the Nuclear Import Receptor Importin Alpha in Complex with the Bipartite NLS of Prp20
por: Roman, Noelia, et al.
Publicado: (2013)

An actin-regulated importin α/β-dependent extended bipartite NLS directs nuclear import of MRTF-A
por: Pawłowski, Rafał, et al.
Publicado: (2010)

Functional exchangeability of the nuclear localization signal (NLS) of capsid protein between PCV1 and PCV2 in vitro: Implications for the role of NLS in viral replication
por: Shuai, Jiangbing, et al.
Publicado: (2011)

Identification of a non-canonical nuclear localization signal (NLS) in BRCA1 that could mediate nuclear localization of splice variants lacking the classical NLS
por: Korlimarla, Aruna, et al.
Publicado: (2013)

At R702
Publicado: (1977)

(702) WITHDRAWN
Publicado: (2023)

NLS-tagging: an alternative strategy to tag nuclear proteins
por: Giraud, Guillaume, et al.
Publicado: (2014)

Affinity for DNA Contributes to NLS Independent Nuclear Localization of MeCP2
por: Lyst, Matthew J., et al.
Publicado: (2018)

Semiclassical focussing NLS
por: Kamvissis, S
Publicado: (2003)

Tyrosine Phosphorylation in the C-Terminal Nuclear Localization and Retention Signal (C-NLS) of the EWS Protein
por: Leemann-Zakaryan, Ruzanna P., et al.
Publicado: (2011)

Evolutionary gradient of predicted nuclear localization signals (NLS)-bearing proteins in genomes of family Planctomycetaceae
por: Guo, Min, et al.
Publicado: (2017)

Semiclassical NLS on the half line
por: Kamvissis, S
Publicado: (2002)

SeqNLS: Nuclear Localization Signal Prediction Based on Frequent Pattern Mining and Linear Motif Scoring
por: Lin, Jhih-rong, et al.
Publicado: (2013)

Coupling of Polo kinase activation to nuclear localization by a bifunctional NLS is required during mitotic entry
por: Kachaner, David, et al.
Publicado: (2017)

On the question of analyticity of data for semiclassical NLS
por: Kamvissis, S
Publicado: (2001)

On the question of analyticity of data for semiclassical NLS
por: Kamvissis, S
Publicado: (2002)

702 A Bone of Contention for Culture Selection
por: Avasarala, Sameer, et al.
Publicado: (2014)

In vivo characterization of chimeric PCV DNA clones containing heterogeneous capsid protein nuclear localization signals (NLS)
por: Shuai, Jiangbing, et al.
Publicado: (2013)

Regulation of Gli ciliary localization and Hedgehog signaling by the PY-NLS/karyopherin-β2 nuclear import system
por: Han, Yuhong, et al.
Publicado: (2017)

CompTIA A+: 220-701 and 220-702
por: Prowse, David L
Publicado: (2011)

Antifungalmycin, an antifungal macrolide from Streptomyces padanus 702
por: Wang, Yi-Fen, et al.
Publicado: (2012)

Insights from the Molecular Modelling and Docking Analysis of AIF-NLS complex to infer Nuclear Translocation of the Protein
por: Srivaths, Akash, et al.
Publicado: (2018)

Odevixibat Treatment of Alagille Syndrome: A Case Report
por: Ganschow, Rainer, et al.
Publicado: (2023)

Acetylation of the nuclear localization signal in Ku70 diminishes the interaction with importin-α
por: Fujimoto, Hirofumi, et al.
Publicado: (2022)

Nuclear localization of mouse Ku70 in interphase cells and focus formation of mouse Ku70 at DNA damage sites immediately after irradiation
por: KOIKE, Manabu, et al.
Publicado: (2015)

A variational problem related to semiclassical focusing NLS
por: Kamvissis, S
Publicado: (2002)

NLS-RARα is a novel transcriptional factor
por: Jiang, Kai-Ling, et al.
Publicado: (2017)

Nuclear spreads: I. Visualization of bipartite ribosomal RNA domains
Publicado: (1995)

Plasmid DNA delivery into MDA-MB-453 cells mediated by recombinant Her-NLS fusion protein
por: Jeyarajan, Sivakumar, et al.
Publicado: (2010)

Run no. 702, 31.3.76, Ring 1, Deuterons
por: Ciapala, Edmond, et al.
Publicado: (1976)

702 Postpartum depression screening during the COVID-19 pandemic
por: Sangtani, Ajleeta, et al.
Publicado: (2021)

702 Hydroxycobalamin is An Independent Risk Factor for Acute Kidney Injury.
por: Gondek, Stephen, et al.
Publicado: (2023)

The poset of bipartitions
por: Hetyei, Gábor, et al.
Publicado: (2011)

FUS-NLS/Transportin 1 Complex Structure Provides Insights into the Nuclear Targeting Mechanism of FUS and the Implications in ALS
por: Niu, Chunyan, et al.
Publicado: (2012)

Importin alpha binding and nuclear localization of PARP-2 is dependent on lysine 36, which is located within a predicted classical NLS
por: Haenni, Sandra S, et al.
Publicado: (2008)

Identification of a Classical Bipartite Nuclear Localization Signal in the Drosophila TEA/ATTS Protein Scalloped
por: Magico, Adam C., et al.
Publicado: (2011)

Human-derived NLS enhance the gene transfer efficiency of chitosan
por: Bitoque, Diogo B., et al.
Publicado: (2021)

Retraction: Self-association of L-periaxin occurs via its acidic domain and NLS2/NLS3, and affects its trafficking in RSC96 cells
por: Yang, Yenan, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_5cjmt5sldpr49e5f9c3323tep9