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Myosin IIA Modulates T Cell Receptor Transport and CasL Phosphorylation during Early Immunological Synapse Formation

Activation of T cell receptor (TCR) by antigens occurs in concert with an elaborate multi-scale spatial reorganization of proteins at the immunological synapse, the junction between a T cell and an antigen-presenting cell (APC). The directed movement of molecules, which intrinsically requires physic...

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Detalles Bibliográficos
Autores principales: Yu, Yan, Fay, Nicole C., Smoligovets, Alexander A., Wu, Hung-Jen, Groves, Jay T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275606/
https://www.ncbi.nlm.nih.gov/pubmed/22347397
http://dx.doi.org/10.1371/journal.pone.0030704