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Silencing of insulin receptor substrate–1 increases cell death in retinal Müller cells

PURPOSE: To determine whether β-adrenergic receptors require insulin receptor substrate (IRS)-1 activity to regulate apoptosis in retinal Müller cells. METHODS: Müller cells were cultured in Dulbecco's Modified Eagle Medium (DMEM) medium grown in normal (5 mm) or high glucose (25 mM) conditions...

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Detalles Bibliográficos
Autores principales: Walker, Robert J., Anderson, Nancy M., Bahouth, Suleiman, Steinle, Jena J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275635/
https://www.ncbi.nlm.nih.gov/pubmed/22328823