Variations in LOXL1 associated with exfoliation glaucoma do not affect amine oxidase activity

PURPOSE: Lysyl oxidase-like 1 (LOXL1) is a copper-dependant amine oxidase that plays an essential role in elastogenesis. Two non-synonymous single-nucleotide polymorphisms of LOXL1, R141L (rs1048661) and G153D (rs3825942), have been reported to significantly increase susceptibility to exfoliation gl...

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Detalles Bibliográficos
Autores principales: Kim, Seonkwan, Kim, Youngho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275637/
https://www.ncbi.nlm.nih.gov/pubmed/22328822

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275637/
https://www.ncbi.nlm.nih.gov/pubmed/22328822

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