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Anti-CD137 mAb Deletes Both Donor CD4(+) and CD8(+) T Cells in Acute Graft-versus-host Disease
We previously demonstrated that in vivo engagement of CD137, a member of TNF receptor superfamily, can delete allorective CD4(+) T cells through the induction of activation-induced cell death (AICD) in chronic graft-versus-host disease (cGVHD) and subsequently reverse established cGVHD. In this stud...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Association of Immunologists
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275716/ https://www.ncbi.nlm.nih.gov/pubmed/22346787 http://dx.doi.org/10.4110/in.2011.11.6.428 |