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Engineering yield and rate of reductive biotransformation in Escherichia coli by partial cyclization of the pentose phosphate pathway and PTS-independent glucose transport

Optimization of yields and productivities in reductive whole-cell biotransformations is an important issue for the industrial application of such processes. In a recent study with Escherichia coli, we analyzed the reduction of the prochiral β-ketoester methyl acetoacetate by an R-specific alcohol de...

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Detalles Bibliográficos
Autores principales: Siedler, Solvej, Bringer, Stephanie, Blank, Lars M., Bott, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275745/
https://www.ncbi.nlm.nih.gov/pubmed/22002070
http://dx.doi.org/10.1007/s00253-011-3626-3