Systemic scAAV9 variant mediates brain transduction in newborn rhesus macaques

Transgenic macaques would allow to study brain function and diseases. We report that an engineered adeno-associated virus serotype 9 variant (scAAV9) injected intravenously in newborn rhesus macaques results in efficient, exclusively-neuronal and widespread transduction of the brain. The present dat...

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Detalles Bibliográficos
Autores principales: Dehay, Benjamin, Dalkara, Deniz, Dovero, Sandra, Li, Qin, Bezard, Erwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275921/
https://www.ncbi.nlm.nih.gov/pubmed/22355765
http://dx.doi.org/10.1038/srep00253

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275921/
https://www.ncbi.nlm.nih.gov/pubmed/22355765
http://dx.doi.org/10.1038/srep00253

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