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Challenges encountered with argatroban anticoagulation during cardiopulmonary bypass

Use of argatroban as an alternative to heparin during cardiopulmonary bypass (CPB) in patients with heparin-induced thrombocytopenia has gained some attention in the past two decades. Dosing of argatroban during CPB is complex due to lack of complete understanding of its pharmacokinetic profile and...

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Detalles Bibliográficos
Autores principales: Agarwal, Shvetank, Ullom, Beth, Al-Baghdadi, Yasser, Okumura, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275940/
https://www.ncbi.nlm.nih.gov/pubmed/22345956
http://dx.doi.org/10.4103/0970-9185.92458