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MRP8/ABCC11 Expression Is Regulated by Dexamethasone in Breast Cancer Cells and Is Associated to Progesterone Receptor Status in Breast Tumors

The ATP-binding cassette multidrug resistance protein 8 (MRP8/ABCC11) mediates the excretion of anticancer drugs. ABCC11 mRNA and protein levels were enhanced by DEX (dexamethasone) and by PROG (progesterone) in MCF7 (progesterone receptor-(PR-) positive) but not in MDA-MB-231 (PR-negative) breast c...

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Detalles Bibliográficos
Autores principales: Honorat, Mylène, Mesnier, Aurélia, Vendrell, Julie, Di Pietro, Attilio, Lin, Valérie, Dumontet, Charles, Cohen, Pascale, Payen, Léa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275985/
https://www.ncbi.nlm.nih.gov/pubmed/22332017
http://dx.doi.org/10.4061/2011/807380