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Additive In Vitro Antiplasmodial Effect of N-Alkyl and N-Benzyl-1,10-Phenanthroline Derivatives and Cysteine Protease Inhibitor E64

Potential new targets for antimalarial chemotherapy include parasite proteases, which are required for several cellular functions during the Plasmodium falciparum life cycle. Four new derivatives of N-alkyl and N-benzyl-1,10-phenanthroline have been synthesized. Those are (1)-N-methyl-1,10-phenanthr...

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Detalles Bibliográficos
Autores principales: Wijayanti, Mahardika Agus, Sholikhah, Eti Nurwening, Hadanu, Ruslin, Jumina, Jumina, Supargiyono, Supargiyono, Mustofa, Mustofa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275986/
https://www.ncbi.nlm.nih.gov/pubmed/22332022
http://dx.doi.org/10.4061/2010/540786