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Liquid chromatographic estimation of (S) - glycidyl butyrate in (R) - glycidyl butyrate

AIM: The present study was undertaken out of a commercial need for the synthesis of Linezolid with impurity limits within the specification. MATERIALS AND METHODS: (R)-Glycidyl butyrate (RGB) is raw material for the synthesis of Linezolid drug substance. This RGB contains (S)-(+)-Glycidyl butyrate (...

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Detalles Bibliográficos
Autores principales: Khan, Mubeen Ahmad, Sinha, Sukumar, Khandekar, Nandkumar, Parashar, Vikas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276010/
https://www.ncbi.nlm.nih.gov/pubmed/22346232
http://dx.doi.org/10.4103/0976-9668.92331