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Liquid chromatographic estimation of (S) - glycidyl butyrate in (R) - glycidyl butyrate
AIM: The present study was undertaken out of a commercial need for the synthesis of Linezolid with impurity limits within the specification. MATERIALS AND METHODS: (R)-Glycidyl butyrate (RGB) is raw material for the synthesis of Linezolid drug substance. This RGB contains (S)-(+)-Glycidyl butyrate (...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276010/ https://www.ncbi.nlm.nih.gov/pubmed/22346232 http://dx.doi.org/10.4103/0976-9668.92331 |