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Formation of the 42-mer Amyloid β Radical and the Therapeutic Role of Superoxide Dismutase in Alzheimer's Disease

Oxidative stress is closely involved in age-related diseases and ageing itself. There is evidence of the leading contribution of oxidative damage to neurodegenerative disease, in contrast to other diseases where oxidative stress plays a secondary role. The 42-mer amyloid β (Aβ42) peptide is thought...

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Detalles Bibliográficos
Autores principales: Murakami, Kazuma, Shimizu, Takahiko, Irie, Kazuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276080/
https://www.ncbi.nlm.nih.gov/pubmed/22332002
http://dx.doi.org/10.4061/2011/654207