17α-Ethynyl-5α-androstane-3α, 17β-diol Treatment of MNU-Induced Mammary Cancer in Rats

N-methyl-N-nitrosourea (MNU) induces estrogen-dependent mammary tumors in female Lewis rats. We explored the antineoplastic activity of a synthetic androstane derivative, 17α-ethynyl-5α-androstane-3α, 17β-diol (HE3235), as a single agent or in combination with docetaxel compared to tamoxifen, anastr...

Descripción completa

Detalles Bibliográficos
Autores principales: Ahlem, Clarence N., Frincke, James M., White, Steven K., Reading, Christopher L., Trauger, Richard J., Lakshmanaswamy, Rajkumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276108/
https://www.ncbi.nlm.nih.gov/pubmed/22332014
http://dx.doi.org/10.4061/2011/618757

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276108/
https://www.ncbi.nlm.nih.gov/pubmed/22332014
http://dx.doi.org/10.4061/2011/618757

Ejemplares similares