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The Catalytic Machinery of a Key Enzyme in Amino Acid Biosynthesis

The aspartate pathway of amino acid biosynthesis is essential for all microbial life but is absent in mammals. Characterizing the enzyme-catalyzed reactions in this pathway can identify new protein targets for the development of antibiotics with unique modes of action. The enzyme aspartate β-semiald...

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Detalles Bibliográficos
Autores principales: Viola, Ronald E., Faehnle, Christopher R., Blanco, Julio, Moore, Roger A., Liu, Xuying, Arachea, Buenafe T., Pavlovsky, Alexander G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276109/
https://www.ncbi.nlm.nih.gov/pubmed/22332000
http://dx.doi.org/10.4061/2011/352538