Cargando…

Genotype Imputation with Thousands of Genomes

Genotype imputation is a statistical technique that is often used to increase the power and resolution of genetic association studies. Imputation methods work by using haplotype patterns in a reference panel to predict unobserved genotypes in a study dataset, and a number of approaches have been pro...

Descripción completa

Detalles Bibliográficos
Autores principales: Howie, Bryan, Marchini, Jonathan, Stephens, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276165/
https://www.ncbi.nlm.nih.gov/pubmed/22384356
http://dx.doi.org/10.1534/g3.111.001198