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Genotype Imputation with Thousands of Genomes
Genotype imputation is a statistical technique that is often used to increase the power and resolution of genetic association studies. Imputation methods work by using haplotype patterns in a reference panel to predict unobserved genotypes in a study dataset, and a number of approaches have been pro...
Autores principales: | Howie, Bryan, Marchini, Jonathan, Stephens, Matthew |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276165/ https://www.ncbi.nlm.nih.gov/pubmed/22384356 http://dx.doi.org/10.1534/g3.111.001198 |
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