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Use of Cumulative Poisson Probability Distribution as an Estimator of the Recombination Rate in an Expanding Population: Example of the Macaca fascicularis Major Histocompatibility Complex

We describe a method to estimate the rate of recombination per generation from the genotypes of a large individual sample of an expanding population, for which the founding event is dated. The approach is illustrated with an application to estimating the major histocompatibility complex (MHC) recomb...

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Detalles Bibliográficos
Autores principales: Blancher, Antoine, Aarnink, Alice, Savy, Nicolas, Takahata, Naoyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276188/
https://www.ncbi.nlm.nih.gov/pubmed/22384389
http://dx.doi.org/10.1534/g3.111.001248