Pancreatic endocrine tumours: mutational and immunohistochemical survey of protein kinases reveals alterations in targetable kinases in cancer cell lines and rare primaries

Background: Kinases represent potential therapeutic targets in pancreatic endocrine tumours (PETs). Patients and methods: Thirty-five kinase genes were sequenced in 36 primary PETs and three PET cell lines: (i) 4 receptor tyrosine kinases (RTK), epithelial growth factor receptor (EGFR), human epider...

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Detalles Bibliográficos
Autores principales: Corbo, V., Beghelli, S., Bersani, S., Antonello, D., Talamini, G., Brunelli, M., Capelli, P., Falconi, M., Scarpa, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276319/
https://www.ncbi.nlm.nih.gov/pubmed/21447618
http://dx.doi.org/10.1093/annonc/mdr048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276319/
https://www.ncbi.nlm.nih.gov/pubmed/21447618
http://dx.doi.org/10.1093/annonc/mdr048

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