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Comparison of Skeletal Effects of Ovariectomy Versus Chemically Induced Ovarian Failure in Mice

Bone loss associated with menopause leads to an increase in skeletal fragility and fracture risk. Relevant animal models can be useful for evaluating the impact of ovarian failure on bone loss. A chemically induced model of menopause in which mice gradually undergo ovarian failure yet retain residua...

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Detalles Bibliográficos
Autores principales: Wright, Laura E, Christian, Patricia J, Rivera, Zelieann, Van Alstine, William G, L Funk, Janet, L Bouxsein, Mary, Hoyer, Patricia B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons and The American Society for Bone and Mineral Research (ASBMR) 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276352/
https://www.ncbi.nlm.nih.gov/pubmed/18348702
http://dx.doi.org/10.1359/jbmr.080309