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Where Wnts Went: The Exploding Field of Lrp5 and Lrp6 Signaling in Bone
Wnt signaling has emerged as a central regulator of skeletal modeling and remodeling. Loss- or gain-of-function mutations in two Wnt co-receptors, Lrp5 and (more recently) Lrp6, have drawn attention to the importance of the Wnt pathway in bone biology. This review summarizes our current understandin...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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John Wiley and Sons and The American Society for Bone and Mineral Research (ASBMR)
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276354/ https://www.ncbi.nlm.nih.gov/pubmed/19072724 http://dx.doi.org/10.1359/jbmr.081235 |