Ethanol Impairs Estrogen Receptor Signaling Resulting in Accelerated Activation of Senescence Pathways, Whereas Estradiol Attenuates the Effects of Ethanol in Osteoblasts

Epidemiological and animal studies have suggested that chronic alcohol consumption is a major risk factor for osteoporosis. Using bone from cycling female rats infused chronically with ethanol (EtOH) in vivo and osteoblastic cells in vitro, we found that EtOH significantly increased estrogen recepto...

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Detalles Bibliográficos
Autores principales: Chen, Jin-Ran, Lazarenko, Oxana P, Haley, Rani Lynn, Blackburn, Michael L, Badger, Thomas M, Ronis, Martin J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons and The American Society for Bone and Mineral Research (ASBMR) 2009
Materias:
Research-Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276356/
https://www.ncbi.nlm.nih.gov/pubmed/18847333
http://dx.doi.org/10.1359/jbmr.081011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276356/
https://www.ncbi.nlm.nih.gov/pubmed/18847333
http://dx.doi.org/10.1359/jbmr.081011

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