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Fibroid explants reveal a higher sensitivity against MDM2-inhibitor nutlin-3 than matching myometrium

BACKGROUND: Spontaneous cessation of growth is a frequent finding in uterine fibroids. Increasing evidence suggests an important role of cellular senescence in this growth control. Deciphering the underlying mechanisms of growth control that can be expected not only to shed light on the biology of t...

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Detalles Bibliográficos
Autores principales: Markowski, Dominique N, Helmke, Burkhard M, Radtke, Arlo, Froeb, Jennifer, Belge, Gazanfer, Bartnitzke, Sabine, Wosniok, Werner, Czybulka-Jachertz, Iris, Deichert, Ulrich, Bullerdiek, Jörn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276409/
https://www.ncbi.nlm.nih.gov/pubmed/22233735
http://dx.doi.org/10.1186/1472-6874-12-2