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Fibroid explants reveal a higher sensitivity against MDM2-inhibitor nutlin-3 than matching myometrium
BACKGROUND: Spontaneous cessation of growth is a frequent finding in uterine fibroids. Increasing evidence suggests an important role of cellular senescence in this growth control. Deciphering the underlying mechanisms of growth control that can be expected not only to shed light on the biology of t...
Autores principales: | Markowski, Dominique N, Helmke, Burkhard M, Radtke, Arlo, Froeb, Jennifer, Belge, Gazanfer, Bartnitzke, Sabine, Wosniok, Werner, Czybulka-Jachertz, Iris, Deichert, Ulrich, Bullerdiek, Jörn |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276409/ https://www.ncbi.nlm.nih.gov/pubmed/22233735 http://dx.doi.org/10.1186/1472-6874-12-2 |
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