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Risk variants in BMP4 promoters for nonsyndromic cleft lip/palate in a Chilean population

BACKGROUND: Bone morphogenetic protein 4 gene (BMP4) plays a key role during maxillofacial development, since orofacial clefts are observed in animals when this gene is conditionally inactivated. We recently reported the existence of association between nonsyndromic cleft lip/palate (NSCLP) and BMP4...

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Detalles Bibliográficos
Autores principales: Suazo, José, Tapia, Julio C, Santos, José Luis, Castro, Víctor G, Colombo, Alicia, Blanco, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276445/
https://www.ncbi.nlm.nih.gov/pubmed/22182590
http://dx.doi.org/10.1186/1471-2350-12-163