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Signatures of positive selection in Toll-like receptor (TLR) genes in mammals

BACKGROUND: Toll-like receptors (TLRs) are a major class of pattern recognition receptors (PRRs) expressed in the cell surface or membrane compartments of immune and non-immune cells. TLRs are encoded by a multigene family and represent the first line of defense against pathogens by detecting foreig...

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Detalles Bibliográficos
Autores principales: Areal, Helena, Abrantes, Joana, Esteves, Pedro J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276489/
https://www.ncbi.nlm.nih.gov/pubmed/22185391
http://dx.doi.org/10.1186/1471-2148-11-368