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Signatures of positive selection in Toll-like receptor (TLR) genes in mammals
BACKGROUND: Toll-like receptors (TLRs) are a major class of pattern recognition receptors (PRRs) expressed in the cell surface or membrane compartments of immune and non-immune cells. TLRs are encoded by a multigene family and represent the first line of defense against pathogens by detecting foreig...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276489/ https://www.ncbi.nlm.nih.gov/pubmed/22185391 http://dx.doi.org/10.1186/1471-2148-11-368 |