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Using Functional Signatures to Identify Repositioned Drugs for Breast, Myelogenous Leukemia and Prostate Cancer

The cost and time to develop a drug continues to be a major barrier to widespread distribution of medication. Although the genomic revolution appears to have had little impact on this problem, and might even have exacerbated it because of the flood of additional and usually ineffective leads, the em...

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Detalles Bibliográficos
Autores principales: Shigemizu, Daichi, Hu, Zhenjun, Hung, Jui-Hung, Huang, Chia-Ling, Wang, Yajie, DeLisi, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276504/
https://www.ncbi.nlm.nih.gov/pubmed/22346740
http://dx.doi.org/10.1371/journal.pcbi.1002347