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Using Functional Signatures to Identify Repositioned Drugs for Breast, Myelogenous Leukemia and Prostate Cancer
The cost and time to develop a drug continues to be a major barrier to widespread distribution of medication. Although the genomic revolution appears to have had little impact on this problem, and might even have exacerbated it because of the flood of additional and usually ineffective leads, the em...
Autores principales: | Shigemizu, Daichi, Hu, Zhenjun, Hung, Jui-Hung, Huang, Chia-Ling, Wang, Yajie, DeLisi, Charles |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276504/ https://www.ncbi.nlm.nih.gov/pubmed/22346740 http://dx.doi.org/10.1371/journal.pcbi.1002347 |
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