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Kosmotropic Anions Promote Conversion of Recombinant Prion Protein into a PrP(Sc)-Like Misfolded Form
Prions are self-propagating proteins involved in transmissible spongiform encephalopaties in mammals. An aberrant conformation with amyloid-like features of a cell surface protein, termed prion protein (PrP), is thought to be the essential component of the infectious particle, though accessory co-fa...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276510/ https://www.ncbi.nlm.nih.gov/pubmed/22347503 http://dx.doi.org/10.1371/journal.pone.0031678 |