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Kosmotropic Anions Promote Conversion of Recombinant Prion Protein into a PrP(Sc)-Like Misfolded Form

Prions are self-propagating proteins involved in transmissible spongiform encephalopaties in mammals. An aberrant conformation with amyloid-like features of a cell surface protein, termed prion protein (PrP), is thought to be the essential component of the infectious particle, though accessory co-fa...

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Detalles Bibliográficos
Autores principales:	Diaz-Espinoza, Rodrigo, Mukherjee, Abhisek, Soto, Claudio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276510/ https://www.ncbi.nlm.nih.gov/pubmed/22347503 http://dx.doi.org/10.1371/journal.pone.0031678

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