Mass Homozygotes Accumulation in the NCI-60 Cancer Cell Lines As Compared to HapMap Trios, and Relation to Fragile Site Location

Runs of homozygosity (ROH) represents extended length of homozygotes on a long genomic distance. In oncology, it is known as loss of heterozygosity (LOH) if identified exclusively in cancer cell rather than in matched control cell. Studies have identified several genomic regions which show consisten...

Descripción completa

Detalles Bibliográficos
Autores principales: Ruan, Xiaoyang, Kocher, Jean-Pierre A., Pommier, Yves, Liu, Hongfang, Reinhold, William C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276511/
https://www.ncbi.nlm.nih.gov/pubmed/22347499
http://dx.doi.org/10.1371/journal.pone.0031628

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276511/
https://www.ncbi.nlm.nih.gov/pubmed/22347499
http://dx.doi.org/10.1371/journal.pone.0031628

Ejemplares similares