Neurophysiological Defects and Neuronal Gene Deregulation in Drosophila mir-124 Mutants

miR-124 is conserved in sequence and neuronal expression across the animal kingdom and is predicted to have hundreds of mRNA targets. Diverse defects in neural development and function were reported from miR-124 antisense studies in vertebrates, but a nematode knockout of mir-124 surprisingly lacked...

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Detalles Bibliográficos
Autores principales: Sun, Kailiang, Westholm, Jakub Orzechowski, Tsurudome, Kazuya, Hagen, Joshua W., Lu, Yubing, Kohwi, Minoree, Betel, Doron, Gao, Fen-Biao, Haghighi, A. Pejmun, Doe, Chris Q., Lai, Eric C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276548/
https://www.ncbi.nlm.nih.gov/pubmed/22347817
http://dx.doi.org/10.1371/journal.pgen.1002515

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276548/
https://www.ncbi.nlm.nih.gov/pubmed/22347817
http://dx.doi.org/10.1371/journal.pgen.1002515

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